A woman has died in a single vehicle crash in Desailly, 96 kilometres north of Mareeba on Sunday afternoon.
Just before 4pm, a Toyota Hilux was traveling along the Mulligan Highway when it left the road and rolled over Harbord Creek Bridge at Desailly.
The female driver died at the scene.
A 58-year-old male passenger was airlifted to Cairns Hospital with head injuries while a 15-year-old female passenger was taken to Mareeba Hospital and then transported to Cairns.
Forensic Crash Unit investigations are underway.